Prof.in Dr. Carole Leguy

Carole Leguy has been Professor of Regulatory Affairs in Medical Technology at Hochschule Ruhr West since 2018. As an internationally oriented scientist, she has gained extensive experience in the field of medical technology. Currently, she focuses on new approaches to “serious games” in rehabilitation for physiotherapy and conducts research in biomedical engineering, with a special emphasis on cardiovascular biomechanics.

In 2017, Carole Leguy led an international research project at RWTH Aachen as part of a bed rest study commissioned by the European Space Agency (ESA). The study investigated the risk to astronauts of how movement restrictions affect vascular ageing, aiming to better understand this process.

Prior to this, she specialised in space physiology at the German Aerospace Center (Institute of Aerospace Medicine) in Cologne and at Simon Fraser University in Vancouver, Canada. She completed her PhD at TU Eindhoven (Netherlands). Her dissertation focused on developing new methods based on ultrasound imaging and patient-specific 1D/3D computational fluid dynamics simulations to improve prevention of cardiovascular diseases such as arteriosclerosis.

Carole Leguy is the recipient of two prestigious European fellowships: the Marie Curie Early Stage Research Fellowship and the International Outgoing Fellowship (IOF).

• Introduction to Medical Informatics in the Bachelor’s Programme in Health and Medical Technologies
• Quality and Life Cycle Management in Healthcare in the Bachelor’s Programme in Health and Medical Technologies
• Cost Structures in Healthcare, Hospital Management in the Bachelor’s Programme in Health and Medical Technologies
• Safety in Healthcare and Medical Product Law in the Bachelor’s Programme in Health and Medical Technologies
• Modelling and Simulation in Medical Technology in the Bachelor’s Programme in Health and Medical Technologies
• Healthcare Management Project Work in the Bachelor’s Programme in Health and Medical Technologies

Selected Journal and Conference Papers

• Frett, T., Petrat, G., Arz, M. et C.A.D. Leguy, Quantitative Evaluation of a Telerobotic System for Vascular Ultrasound Measurement on a Short Arm Human Centrifuge, Microgravity Sci. Technol. 33 (14), 2021.

• J.M.T. Keijsers, C.A.D. Leguy, W. Huberts, A.J. Narracott, J. Ritweger, F.N.V.D Vosse, Modeling regulation of vascular tone following muscle contraction: model development, validation and global sensitivity analysis, Journal of Computational Science, 24, 143-159, 2018.

• C.A.D. Leguy, R. Delfos, M.J.B.M. Pourquie, C. Poelma, J. Westerweel, J.J.W.A. van Loon, Fluid dynamics during Random Positioning Machine micro-gravity experiments, Advances in Space Research, 59(12), 3045-3057, 2017.

• J.M.T. Keijsers, C.A.D. Leguy, W. Huberts, A.J. Narracott, J. Ritweger, F.N.V.D Vosse, Global sensitivity analysis of a model for venous valve dynamics, Journal of Biomechanics, 49(13), 2845-2853, 2016.

• J.M.T. Keijsers, C.A.D. Leguy, W. Huberts, A.J. Narracott, J. Ritweger, F.N.V.D Vosse, A 1D pulse wave propagation model of the hemodynamics of calf muscle pump function, Int. J. Numer. Meth. Biomed. Engng., e02714, 2015.

• C.A.D. Leguy, P. Beck, P. Gauger, L. Beck, U. Limper,Carotid arterial wall dynamics during gravity changes on partial-g parabolic flights, Microgravity Science and Technology, Vol 26 (2), pp.111-117, 2014.

• C.A.D Leguy, E.M.H. Bosboom, A. Belloum, A.P.G. Hoeks, F.N van de Vosse, Global sensitivity analysis of a wave propagation model for arm arteries, Medical Engineering & Physics, Vol 33 (8), pp.1008-1016, 2011.

• C.A.D. Leguy, E.M.H. Bosboom, H. Gelderblom, F.N. van de Vosse, Estimation of distributed arterial mechanical properties using a wave propagation model in a reverse way, Medical Engineering & Physics, Vol. 32(9), pp. 957-67, 2010.

• C.A.D. Leguy, E.M.H. Bosboom, A.P.G Hoeks , F.N. van de Vosse, Model based assessment of dynamic arterial blood volume flow from ultrasound measurements, Medical & Biological Engineering & Computing, Vol. 47, pp. 641-648, 2009.

• C.A.D. Leguy, E.M.H. Bosboom, A.P.G Hoeks , F.N. van de Vosse, Assessment of blood volume flow in slightly curved arteries from a single velocity profile, Journal of Biomechanics, Vol. 42, pp. 1664-1672, 2009.

• A.A. Arntzen-Bechina and C.A.D. Leguy, An Insight into Knowledge Flow in Biomedical Engineering Science, The Electronic Journal of Knowledge Management, Vol. 5 (2), pp. 153-160, 2007

• A.A. Arntzen-Bechina and C.A.D.Leguy, A Model of Knowledge Sharing in Biomedical Engineering: Challenges and Requirements, Journal of Business Chemistry Vol. 4 (1), 2007

PhD Thesis

• C.A.D. Leguy, On the clinical estimation of the hemodynamical and mechanical properties of the arterial tree, Technological University of Eindhoven, ISBN: 978-90-386-2342-9, 2010

          Buchkapitel

• C.A.D.Leguy, Cardiovascular computing: methodologies and clinical applications. Chapter: Mathematical and computational modelling, Springer, ISBN 978-981-10-5092-3, 2018

Publication Lists

Google Scholar: https://scholar.google.com/citations?user=bdAwrcoAAAAJ&hl=de